Which of the following is a sign that might indicate infection in a wound?

A foul odor emanating from a wound is a significant sign that may indicate infection. When bacteria proliferate in a wound, they can produce various substances that lead to an unpleasant smell. This odor is often associated with the breakdown of tissue and the presence of pus or necrotic (dead) tissue, both of which can occur in infected wounds. The presence of a foul smell serves as a critical indicator for healthcare providers to assess the wound further, implement appropriate care, and possibly initiate treatment measures to combat the infection.

The other signs listed do not universally signify infection. While a bright red color may indicate healthy granulation tissue or, in some cases, an inflammatory response, it is not inherently a sign of infection. Moderate swelling can occur with inflammation, which is part of the healing process, and does not necessarily mean that infection is present. Likewise, the absence of pain can occur in various wound types, including those that are healing properly, making it insufficient to determine the presence or absence of infection.