What does eschar consist of?

Eschar primarily consists of denatured protein, which forms as a result of tissue damage and necrosis. When the skin or underlying tissues are injured, especially in cases such as burns, pressure ulcers, or other types of wounds, the cells and proteins break down. This process leads to the formation of a hardened, dark scab-like structure known as eschar.

The composition of eschar reflects the coagulation and necrotic processes that occur in the damaged tissue. When proteins within the cells are denatured due to heat, trauma, or lack of blood supply, they create a protective barrier over the wound, although it can also impede the healing process by preventing the underlying tissue from receiving necessary nutrients and moisture.

In contrast, fibrous connective tissue, fatty tissue, and granulation tissue refer to different aspects of wound healing and tissue structure. Fibrous connective tissue is essential for structural support and repair, while fatty tissue serves as insulation and energy storage. Granulation tissue forms during the healing process, consisting of new connective tissue and blood vessels that develop at the site of injury, which is distinct from the necrotic nature of eschar. Thus, understanding the makeup of eschar being primarily denatured protein is crucial in recognizing its